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Modified Chang system for staging of medulloblastoma

Modified Chang system for staging of medulloblastoma
Extent of tumor*
T1 Tumor less than 3 cm in diameter
T2 Tumor greater than 3 cm in diameter
T3a Tumor greater than 3 cm in diameter with extension into the aqueduct of Sylvius and/or the foramen of Luschka
T3b Tumor greater than 3 cm in diameter with unequivocal extension into the brain stem
T4 Tumor greater than 3 cm in diameter with extension up past the aqueduct of Sylvius and/or down past the foramen magnum
No consideration is given to the number of structures invaded or the presence of hydrocephalus.
T3b can be defined by intraoperative demonstration of tumor extension into the brain stem in the absence of radiographic evidence.
Degree of metastasis
M0 No evidence of gross subarachnoid or hematogenous metastasis
M1 Microscopic tumor cells found in the cerebrospinal fluid
M2 Gross nodular seeding demonstrated in the cerebellar/cerebral subarachnoid space or in the third or lateral ventricles
M3 Gross nodular seeding in the spinal subarachnoid space
M4 Metastasis outside the cerebrospinal axis
* The utility of T staging in the modern era is unclear. Most experts use M staging alone for medulloblastoma.
Adapted from:
  1. Chang CH, Housepian EM, Herbert C Jr. An operative staging system and a megavoltage radiotherapeutic technic for cerebellar medulloblastomas. Radiology 1969; 93:1351.
  2. Cohen ME, Duffner PK (Eds). Brain Tumors in Children, 2nd ed, McGraw-Hill, New York, 1994, p. 187.
Graphic 73044 Version 2.0

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