Declining follicle number with age

A comparison of the relationship between age and primordial follicle number in Block's study of 44 females aged 7 to 44 years with that of Gougeon's study of females aged 45 to 55 years. Follicle depletion appears to accelerate in the decade preceding menopause.

Data from:

Block E. Quantitative morphological investigations of the follicular system in women; variations at different ages. Acta Anat 1952; 14:108.
Gougeon A. Caractères qualitatifs et quantitatifs de la population folliculaire dans lóvaire humain adulte. Contr Fert Sex 1984; 12:527.

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Declining follicle number with age