Syndrome | Flu | Rep | Comp | Read | Write | Localization |
Broca | – | – | + | + | – | "Broca" area: left inferior frontal, often anterior MCA branch occlusion |
Wernicke | + | – | – | – | – | "Wernicke" area: left superior temporal and inferior parietal region, often posterior MCA branch occlusion |
Anomic | + | + | + | ± | ± | Temporal, parietal, and occipital regions of cortex outside of classical language areas |
Conduction | + | – | + | + | ± | Superior temporal gyrus, inferior parietal region adjacent to temporal lobe; classically in arcuate fasciculus |
Transcortical motor | – | + | + | + | – | Left mesial frontal, especially supplementary motor area; anterior cerebral artery occlusion |
Transcortical sensory | + | + | – | – | – | Left posterior watershed zone between MCA and PCA territories |
Transcortical mixed | – | + | – | – | – | Anterior and posterior watershed zones, effectively disconnecting perisylvian cortex from other cortical regions |
Global | – | – | – | – | – | Large MCA or left carotid inclusions infarcting a vast region of the left hemisphere |
Pure word deafness | + | + | – | + | + | Left or bilateral superior temporal gyrus lesions |
Pure alexia | + | + | + | – | + | Left occipital lobe with involvement of splenium of corpus callosum |
Aphemia | – | + | + | + | + | Motor cortex outflow to articulators |
Pure agraphia | + | + | + | + | – | Left inferior frontal region |