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خرید پکیج

تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Common mechanisms of antiseizure medication action

Common mechanisms of antiseizure medication action

Drug	Na+ channels	Ca+ channels	K+ channels	Inhibitory transmission	Excitatory transmission	SV2A binding
Benzodiazepines				+++
Brivaracetam						+++
Cannabidiol				++
Carbamazepine	+++	+
Cenobamate	++			+
Clobazam				+++
Eslicarbazepine	+++
Ethosuximide		+++
Felbamate	++	+		++	++
Gabapentin		++		++
Lacosamide	+++
Lamotrigine	+++	+
Levetiracetam		+	+	+	+	+++
Oxcarbazepine	+++	+	+
Perampanel					+++
Phenobarbital		+		+++	+
Phenytoin	+++	+
Pregabalin		++		++
Primidone		+		+++	+
Rufinamide	+++
Stiripentol				+++
Tiagabine				+++
Topiramate	++	++		++	++
Valproate	+	+		++	+
Vigabatrin				+++
Zonisamide	++	++

+++: primary action; ++: probable action; +: possible action.
SV2A: synaptic vesicle protein 2A.

Adapted with permission from: Brodie MJ, Kwan P. Staged approach to epilepsy management. Neurology 2002; 58:S2. Copyright © 2002 Lippincott Williams & Wilkins.

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