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Guidelines for evaluating the suitability of chemotherapy in elderly patients with CRC

Guidelines for evaluating the suitability of chemotherapy in elderly patients with CRC
Fitness category Criteria Suitability of chemotherapy
Group I: fit Totally independent Full-dose treatment, assuming life expectancy is longer than the life expectancy from cancer
No serious comorbidity
Group II: intermediate Dependent in one or more IADLs or with some comorbidity Consideration of chemotherapy dose reduction for first administration
Group III: frail Dependence in one or more ADLs Not suitable for chemotherapy; supportive care recommended
Three or more comorbid conditions
One or more geriatric syndromes
CRC_chemo_elderly_guide.htm
ADLs: activities of daily living (eg, transferring, grooming, continence, using the toilet, dressing, feeding); IADLs: instrumental activities of daily living (eg, transportation, money management, shopping, taking medications, preparing meals).
Reproduced with permission from: Kohne CH, Folprecht G, Goldberg RM, et al. Chemotherapy in Elderly Patients with Colorectal Cancer. The Oncologist 2008; 13:390. Copyright © 2008 AlphaMed Press.
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