Family history-based estimate of risk of cardiovascular disease

• No known family history, OR

• Only one second-degree relative (or more distantly related relative) affected

• One first-degree relative with disease onset at an average age, OR

• Two affected second-degree relatives on the same side of the family

• Premature disease or unusual presentation in a first-degree relative, OR

• Two or more first-degree relatives on the same side of the family affected, OR

• Two or more second-degree relatives on the same side of the family affected, with at least one having premature disease onset, OR

• Three or more affected on the same side of the family, OR

• Moderate-risk status on both sides of the family