Version May 2024
| Antidote | Poisoning indication | Pediatric dose |
| N-acetylcysteine | Acetaminophen | Oral Loading dose: 140 mg/kg orally; oral maintenance doses: 70 mg/kg every four hours for 17 doses Intravenous (IV) administration: 150mg/kg over 1 hour (loading dose); 50 mg/kg IV over 4 hours; 100 mg/kg IV over 16 hours |
| Atropine | Carbamate insecticide | 0.02 mg/kg IV bolus (0.1 mg minimum dose; maximum single dose 0.5 mg for children and 1.0 mg for adolescents) repeat doses titrated to effect |
| Organophosphate insecticide | ||
| Crotalid antivenin | Crotalid snakes | 4 to 6 vials (more if severe) |
| Calcium gluconate and calcium chloride (10 percent) | Calcium channel blocker | Gluconate: 100 to 200 mg/kg IV Chloride: 20 to 30 mg/kg IV repeat doses and IV infusions are common |
| Hydrogen fluoride (HF) | ||
| Cyanide antidote kit (may contain sodium nitrite 3 percent ,sodium thiosulfate, and/or hydroxocobalamin) | Cyanide | Sodium thiosulfate: 400 mg/kg IV (maximum 12.5 grams) Hydroxocobalamin: 70 mg/kg IV (maximum 5 grams) Sodium nitrite: 6 mg/kg by slow IV infusion (maximum 300 mg, only give if not contraindicated and hydroxocobalamin is not available), refer to UpToDate topics on cyanide poisoning |
| Deferoxamine | Iron | 5 to 15 mg/kg per hour IV infusion, titrated to effect |
| Digoxin immune Fab | Digoxin | Empiric dosing: 10 to 20 vials IV bolus of life-threatening toxicity; see package insert for other dosing regimens |
| Digitoxin | ||
| Natural product (eg, plants, toads) | ||
| Dimercaprol (BAL, British antilewisite) | Acute arsenic | 2.5 to 4 mg/kg IM |
| Inorganic mercury | ||
| Lead (with encephalopathy) |
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