Topical retinoids for treatment of photoaging^[1]

Topical retinoid	Preparations
Tretinoin	Altreno (0.05% lotion) Atralin* (0.05% micronized gel) Avita (0.025% cream and gel) Refissa^¶ (0.05% cream) Renova^¶ (0.02% cream) Retin-A (0.025%, 0.05%, 0.1% cream; 0.01%, 0.025% gel) Retin-A Micro (0.04%, 0.06%, 0.08%, and 0.1% microsphere gel) Generic (0.025%, 0.05%, 0.1% cream; 0.01%, 0.025%, 0.04%, 0.05%, 0.1% gel)
Tazarotene	Arazlo (0.045% lotion) Fabior (0.1% foam) Tazorac (0.05%, 0.1% cream and gel) Generic (0.1% cream)
Adapalene (off-label use)	Differin (0.1% cream, gel, and lotion; 0.3% gel) Differin XP (United States: not available) (0.3% gel) Generic (0.1% cream, gel, pad, and solution; 0.3% gel)

Topical retinoid preparations are used off-label for treatment of photoaging, unless otherwise noted. For additional information including doses, administration, and precautions, refer to the topic review of photoaging and Lexicomp drug monographs included within UpToDate.

FDA: US Food and Drug Administration.
* Contains soluble fish proteins and should be used with caution in patients with known sensitivity or allergy to fish.
¶ FDA-approved as adjunctive treatment for palliation of fine wrinkles (Renova, Refissa), mottled hyperpigmentation, and facial skin roughness (Refissa) in patients who use comprehensive skin care and sun avoidance programs.

Reference:

Chien A, Voorhees JJ, King S. Topical retinoids. In: Fitzpatrick's Dermatology in General Medicine, 8th ed, Goldsmith LA, Katz SI, Gilchrest BA (Ed), McGraw-Hill, 2012.

Graphic 70303 Version 8.0

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Topical retinoids for treatment of photoaging[1]

Topical retinoids for treatment of photoaging^[1]