By CNS depression | Opiates | Barbiturates | Ethanol, ethylene glycol, methanol, isopropyl alcohol | Sedative-hypnotics (usually if co-ingested with another CNS depressant) | Tricyclic antidepressants | Clonidine | By impairing oxygen diffusion | Opiates | Salicylates | Hydrocarbons (aspiration pneumonitis) | Paraquat | Smoke inhalation | Phosgene and chlorine | By complications | Any CNS depressant can result in aspiration. | | By paralysis of the ventilatory muscles | Neuromuscular blockers (pancuronium, vecuronium, succinylcholine, etc.) | Organophosphates and carbamates | Snakebites | Tetanus toxin | Strychnine | Botulinum toxin | Simple asphyxiants (Displace oxygen in the lungs) | Methane | Propane | Nitrogen | Carbon dioxide | Cellular asphyxiants (Inability to deliver or utilize oxygen by the cell) | Carbon monoxide | Cyanide | Hydrogen sulfide | Methemoglobinemia | Sulfhemoglobinemia | |