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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Immunologic synapse

Immunologic synapse
APCs are illustrated as presenting a peptide bound to human leukocyte antigen (HLA) forming an "immunologic synapse" with the T cell immunoreceptor. CD8-positive T cells bind to MHC class I APCs, and CD4-positive T cells bind to MHC class II-positive APCs. Notice the presence of secondary messenger systems such as the CD28 and B7 molecules (CD80/B7-1 and CD86/B7-2), which also come into apposition to allow a T cell response. Local adhesion molecules are thought to help stabilize the synapse.
MHC: major histocompatibility complex; CD: cluster of differentiation; ICAM-1: intercellular adhesion molecule 1; LFA-1: lymphocyte function-associated antigen 1; TCR: T cell receptor.
Graphic 69555 Version 6.0

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