Leukocyte infiltration in COPD

Photomicrograph showing leukocyte infiltration in a small airway of a smoker with severe COPD (A); and that of smoker with a mild COPD (B). Immunostaining with monoclonal antibody anti-CD45. Leukocytes are stained in red. Original magnification: X400.

Reproduced with permission from: Turato G, Zuin R Miniati M et al. Airway inflammation in severe chronic obstructive pulmonary disease: relationship with lung function and radiologic emphysema. Am J Respir Crit Care Med 2002;166:105. Copyright © 2002 American Thoracic Society.

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Leukocyte infiltration in COPD