Small lymphocytes versus large granular lymphocytes
Distinction between small lymphocytes (A) and large granular lymphocytes (B) on blood smears. The large granular lymphocyte is about twice the size of the red cells and has abundant cytoplasm containing azurophilic granules. Micrographs were viewed with a Leica Leitz DMRB microscope using a 100x/1.30 oil immersion objective. Images were captured with a Sony Exwave HAD camera and manipulated using Tribyn Version 1.3 software.
This research was originally published in Blood. Lamy T, Loughran TP Jr. How I treat LGL leukemia. Blood 2011; 117:2764. Copyright © 2011 American Society of Hematology.
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