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Prevalence of thrombophilic defects in venous thrombosis

Prevalence of thrombophilic defects in venous thrombosis
Condition Prevalence, percent*
Activated protein C resistance (factor V Leiden) 12 to 40
Prothrombin G20210A gene mutation 6 to 18
Deficiencies of Antithrombin, protein C, protein S 5 to 15
Antiphospholipid antibody syndrome 5 to 10
* Note: The lower percentage for each condition is for unselected patients; the higher percentage is for those with first events prior to age 50 or with a history of venous thrombosis in first-degree relatives.
¶ Prevalence restricted to White populations.
Graphic 68916 Version 3.0

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