Contraindications | Acute bleeding (eg, hemorrhagic shock, massive hemoptysis) | Multiple fractures or trauma (eg, unstable fractures of femur, pelvis, face) | Spinal instability | Raised intracranial pressure >30 mmHg or cerebral perfusion pressure <60 mmHg | Tracheal surgery or sternotomy within two weeks | Relative contraindications | Shock (eg, persistent mean arterial pressure <65 mmHg) | Anterior chest tube(s) with air leaks* | Major abdominal surgery | Recent pacemaker* | Clinical conditions limiting life expectancy* (eg, oxygen or ventilator-dependent respiratory failure) | Severe burns* | Recent lung transplant recipient* | | Complications | Nerve compression (eg, brachial plexus injury) | Crush injury | Venous stasis (eg, facial edema) | Dislodging endotracheal tube | Diaphragm limitation | Pressure sores (eg, facial) | Dislodging vascular catheters or drainage tubes | Retinal damage | Transient reduction in arterial oxygen saturation | Vomiting | Transient arrhythmias | |