Presence of systemic B symptoms* | ||
Ann Arbor stage III or IV disease | ||
Elevated lactate dehydrogenase | ||
Regional lymph node involvement¶ | ||
One point is given for each of the above characteristics present in the patient, for a total score ranging from zero to four. When applied to retrospective series of patients with extranodal NK/T cell lymphoma, five-year overall survival (OS) and rates of central nervous system (CNS) involvement without prophylaxis according to score were as follows: | ||
Score | OS, percent[1] | CNS involvement, percent[2] |
0 | 81 | <2 |
1 | 64 | <2 |
2 | 34 | <2 |
3 or 4 | 7 | 10 |
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