NCI CTCAE v5.0 acneiform rash

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Acneiform rash	Papules and/or pustules covering <10% of the body surface area, which may or may not be associated with symptoms of pruritus or tenderness	Papules and/or pustules covering 10 to 30% of the body surface area, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL*; papules and/or pustules covering >30% of the body surface area, with or without mild symptoms	Papules and/or pustules covering >30% of the body surface area with moderate or severe symptoms; limiting self-care ADL*; associated with local superinfection with oral antibiotics indicated	Life-threatening consequences; papules and/or pustules covering any percent of the body surface area, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with intravenous antibiotics indicated	Death

Acneiform rash is characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest, and back.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; ADL: activities of daily living.
* Instrumental ADLs include preparing meals, shopping, using the telephone, managing money. Self-care ADLs include bathing, dressing/undressing, using the toilet, taking medications, and not bedridden.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

Graphic 67786 Version 14.0

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NCI CTCAE v5.0 acneiform rash