Diagnostic criteria for Kawasaki disease

The diagnosis of KD requires the presence of fever lasting at least 5 days* without any other explanation combined with at least 4 of the 5 following criteria. A significant proportion of children with KD have a concurrent infection; therefore, ascribing the fever to such an infection or to KD requires clinical judgment.

Bilateral bulbar conjunctival injection

Oral mucous membrane changes, including injected or fissured lips, injected pharynx, or strawberry tongue

Peripheral extremity changes, including erythema of palms or soles, edema of hands or feet (acute phase), and periungual desquamation (convalescent phase)

Polymorphous rash

Cervical lymphadenopathy (at least 1 lymph node >1.5 cm in diameter)

KD: Kawasaki disease.
* If ≥4 of the above criteria are present, a diagnosis of KD can be made on day 4 of illness.

Graphic 67711 Version 9.0

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Diagnostic criteria for Kawasaki disease