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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Antineoplastic drugs that act as vesicants or irritants

Antineoplastic drugs that act as vesicants or irritants
Vesicants
Amsacrine
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Lurbinectedin
Mechlorethamine
Mitomycin
Trabectedin
Vinblastine
Vincristine and liposomal vincristine
Vindesine
Vinorelbine
Irritants
Ado-trastuzumab emtansine*
Bendamustine
Bleomycin
Bortezomib
Busulfan
Carboplatin
Carmustine
CisplatinΔ
Cladribine
Cyclophosphamide
Cytarabine
DacarbazineΔ
Docetaxel
Enfortumab vedotin
Etoposide
Fluorouracil/floxuridine
Gemcitabine
Ifosfamide
Irinotecan
Ixabepilone
Liposomal daunorubicin
Liposomal doxorubicin
Melphalan
Mitoxantrone
Oxaliplatin
Paclitaxel
Paclitaxel, nanoparticle albumin bound (nabpaclitaxel)
Streptozocin
Teniposide
Topotecan

* A single case of skin necrosis after ado-trastuzumab emtansine extravasation has been reported.[1]

¶ Irritants that may cause soft tissue injury when extravasated.

Δ May have vesicant properties depending on the concentration of volume of drug extravasated. As an example, extravasation of a large volume (>20 mL) of concentrated cisplatin (>0.5 mg/mL) may produce tissue necrosis.
Reference:
  1. Shafaee MN, Salahudeen AA, Valero V. Skin Necrosis After Ado-Trastuzumab Emtansine Extravasation. J Oncol Pract 2017; 13:555.
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