Intestine, kidney: energy-dependent sodium/glucose co-transporters |
Other cells: diffusion via GLUTs 1 to 5 |
GLUT-1: All human tissues; high affinity; basal glucose uptake; central nervous system, vessels |
GLUT-2: Beta cells, liver; low-affinity; post-prandial action |
GLUT-3: All tissues; major transporter in neurons of central nervous system |
GLUT-4: Skeletal muscle, fat cells; insulin stimulates translocation from cytosol to cell membranes |
GLUT-5: Brush border of intestinal cells, liver, spermatozoa; primarily transports fructose |
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