Increased potassium secretion in potassium adaptation

Relationship between the plasma potassium concentration (which is raised by potassium chloride infusion) and distal potassium secretion in normal animals (dashed line) and those treated with a high-potassium diet for four weeks (solid line). A high-potassium diet leads to potassium adaptation: at any plasma potassium concentration, distal potassium secretion is two to four times higher in adapted animals compared to normals.