Version June 2024
| Unexplained anemia |
| Macrocytic anemia (to distinguish megaloblastic from normoblastic maturation) |
| Unexplained leukopenia |
| Unexplained thrombocytopenia |
| Pancytopenia |
| Presence of blasts on peripheral smear (investigation for possible leukemia) |
| Presence of teardrop red cells on peripheral smear (possible myelofibrosis) |
| Presence of hairy cells on peripheral smear (possible hairy cell leukemia) |
| Suspected multiple myeloma |
| Staging of non-Hodgkin's lymphoma |
| Unexplained splenomegaly (possible lymphoma) |
| Suspected storage disease (eg, Gaucher disease, Niemann-Pick) |
| Fever of unknown origin |
| Suspected chromosomal disorders in neonates (requiring rapid confirmation) |
| Confirmation of normal marrow in potential allogeneic donor |
| Work-up of amyloidosis (to detect clonal plasma cell disorder) |
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