Metabolic and endocrine |
Hypothalamic-pituitary-adrenal axis suppression |
Hyperglycemia |
Dermatologic and appearance |
Cushingoid features |
Weight gain |
Skin thinning and ecchymoses |
Acne, hirsutism, facial erythema |
Cardiovascular |
Fluid retention |
Hypertension |
Premature atherosclerotic disease and major cardiac events (eg, myocardial infarction, stroke) |
Arrhythmias |
Pulmonary emboli and venous thromboembolism |
Possible hyperlipidemia |
Gastrointestinal |
Gastritis, peptic ulcer disease, and upper gastrointestinal bleeding |
Steatohepatitis |
Visceral perforation |
Bone and muscle effects |
Osteoporosis |
Osteonecrosis/avascular necrosis |
Myopathy |
Neuropsychiatric |
Insomnia |
Depression |
Psychosis |
Memory impairment |
Ophthalmologic |
Cataracts |
Elevated intraocular pressure/glaucoma |
Immune system |
Increased risk of infections |
Decreased response to vaccinations |
Other |
Tooth hypersensitivity |
Epistaxis |
Growth impairment in children |
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