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Dorsal root ganglia in paraneoplastic sensory neuronopathy

Dorsal root ganglia in paraneoplastic sensory neuronopathy
Light micrograph of dorsal root ganglia from a patient with small cell lung cancer, anti-Hu antibodies, and paraneoplastic sensory neuronopathy. There are conspicuous infiltrates of mononuclear cells (arrowhead), with some neurons undergoing degeneration (arrow). There is also proliferation of satellite cells replacing the disappearing neurons, called Nageotte nodules (thick arrows).
Courtesy of Josep Dalmau, MD, PhD.
Graphic 65517 Version 3.0

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