Version May 2024
| 1. How great is the burden of suffering caused by the condition in terms of: |
| Death |
| Disease |
| Disability |
| Discomfort |
| Dissatisfaction |
| Destitution |
| 2. How good is the screening test, if one is to be performed, in terms of: |
| Sensitivity |
| Specificity |
| Simplicity |
| Cost |
| Safety |
| Acceptability |
| 3. A. For primary and tertiary prevention, how good is the therapeutic intervention in terms of: |
| Effectiveness |
| Safety |
| Cost-effectiveness |
| Or |
| 3. B. For secondary prevention, if the condition is found, how good is the ensuing treatment in terms of: |
| Effectiveness |
| Safety |
| Early treatment after screening being more effective than later treatment without screening, when the patient becomes symptomatic |
| Cost-effectiveness |
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