Defective interleukin 17a (IL-17a) expression in hyperimmunoglobulin E syndrome (HIES)

Peripheral blood mononuclear cells (PBMCs) from a healthy individual and an individual with HIES are stimulated to induce IL-17a expression. IL-17 is severely reduced in patients with HIES.

HIES: hyperimmunoglobulin E syndrome; IL-17a: interleukin 17a.

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