Version May 2024
NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; ADL: activities of daily living; CBC: complete blood count; SubQ: subcutaneously; DTO: deodorized tincture of opium; CT: computed tomography; DPD: dihydropyrimidine dehydrogenase; FU: fluorouracil; IV: intravenous; GI: gastroenterology.
* Dose of loperamide should not exceed the daily maximum of 16 mg (8 tablets) in 24 hours due to the risk of cardiac arrhythmias.
¶ Stool workup for infectious cause of diarrhea: testing for Clostridioides (formerly Clostridium) difficile, stool culture (Salmonella species, Shigella species, Escherichia coli, Campylobacter). Patients with bloody diarrhea should be evaluated for enterohemorrhagic E. coli infection and Entamoeba.
Δ Consider CT scan for signs of peritonitis.
◊ Titration up to 2000 micrograms SubQ every 8 hours or use of an IV infusion may be needed in nonresponders (refer to UpToDate topic).آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
