Version May 2024
| Treatment | Adult dose |
| Preferred agents* | |
| Trimethoprim-sulfamethoxazole (cotrimoxazole) | 1 or 2 DS tablets twice daily¶ |
| Clindamycin | 450 mg orally 3 times daily |
| Doxycycline | 100 mg orally twice daily |
| Minocycline | 200 mg orally once, then 100 mg orally twice daily |
| Alternative agentsΔ | |
| Linezolid | 600 mg orally twice daily |
| Tedizolid | 200 mg orally once daily |
| Delafloxacin | 450 mg orally twice daily |
| Omadacycline | 300 mg orally once daily |
DS: double strength (ie, 160 mg trimethoprim with 800 mg sulfamethoxazole per tablet).
* In general, the choice between the preferred oral antibiotic agents is guided by individual clinical circumstances including local antibiotic resistance patterns, allergy history, and concomitant medications.
¶ For patients who weigh more than 70 kg and have normal renal function, the typical dose is two double-strength tablets twice daily.
Δ Use of alternative oral antibiotic agents is limited by cost, clinical experience, and adverse drug effects. They should be reserved for patients who do not respond to or cannot tolerate the preferred agents.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
