Metabolic actions of insulin on lipid and protein metabolism

Glucose metabolism (see text)

Lipid metabolism

Inhibition of lipolysis in fat; decreased plasma fatty acid concentrations

Stimulation of fatty acid and triacylglycerol synthesis in fat and liver

Increased lipoprotein lipase activity in fat; increased triglyceride uptake into fat

Decreased fatty acid oxidation in muscle and liver

Increased rate of formation of very-low-density lipoproteins in liver

Protein metabolism

Increased transport of some amino acids into muscle, adipose tissue, liver and other cells

Increased rate of protein synthesis in muscle, adipose tissue, liver and other tissues

Decreased proteolysis in muscle

Decreased urea formation

Metabolic_actions_insulin.htm

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