Sinusoidal obstruction syndrome

Light micrograph of sinusoidal obstruction syndrome in which venular occlusion has led to widespread zonal liver disruption and centrilobular hemorrhagic necrosis.

Reproduced by permission from: Negrin RS, Blume KG. Bone marrow and peripheral blood progenitor cell transplantation. In: Leukemia, 6th ed, Henderson ES, Lister TA, Greaves ME (Eds), WB Saunders, Philadelphia, 1996. p.389.

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