Extended-interval dosing nomogram for gentamicin and tobramycin*
Extended-interval dosing nomogram for gentamicin and tobramycin*
The serum gentamicin or tobramycin concentration should be obtained 6 hours (or up to 14 hours) after the initial dose of 7 mg/kg and plotted on the above nomogram. The interval for drug administration of subsequent doses of 7 mg/kg is then determined based on the interval specified on the graph.
* Application of the nomogram for amikacin requires the measured concentration be divided by two. The new value should be plotted on the nomogram in order to obtain the appropriate dosing interval.