Plasma norepinephrine and survival in HF

Percent probability of survival in patients with advanced heart failure according to the plasma norepinephrine concentration. Survival was inversely related to the degree of norepinephrine activation, a presumed reflection of worsening cardiac function. The time to 50 percent survival was approximately 30 months in patients with normal norepinephrine levels (200 pg/mL) but only about 10 months in those with marked hypersecretion (1200 pg/mL).