Graph showing determinants of urea clearance during sustained low efficiency dialysis

Relationship among urea clearance, blood flow rate (QB), and dialysate flow rate (QD) during sustained low efficiency dialysis (SLED). The flattening of the urea clearance curves describe the conditions in which increases in QB do not enhance clearance.

QD: dialysate flow rate; QB: blood flow rate.

Data from: Kudoh Y, Imura O. Slow continuous hemodialysis—new therapy for acute renal failure in critically ill patients—Part 1. Theoretical consideration and new technique. Jpn Circ J 1988; 52:1171.

Graphic 60742 Version 3.0

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