Differentiating Parkinson disease and essential tremor

Clinical features	Parkinson disease tremor	Essential tremor
Age at onset	>50 years	Bimodal 2^nd and 6^th decade
Sex	Male ≥ Female	Male = Female
Family history	~10 to 15 percent	~50 percent
Asymmetry	+++	+
Frequency	4 to 6 Hz	6 to 12 Hz
Character	At rest	Postural, kinetic
Character	Supination-pronation	Flexion-extension
Distribution	Hands, legs, chin, tongue	Hands, head, voice
Associated features	Bradykinesia, rigidity, postural instability, micrographia	Mild gait disorder or cerebellar signs in a minority

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