Ability of CARG risk score versus physician-rated Karnofsky performance status (KPS) to predict chemotherapy toxicity

Risk strata	No toxicity		Toxicity		Total	p	ROC
Risk strata	No.	Percent	No.	Percent	Total	p	ROC
By total score
0-5 (low)	89	70	39	30	128	<0.001	0.72*
6-9 (mid)	110	48	117	52	227
10-19 (high)	19	17	90	83	109
By physician-rated KPS (percent)
90-100	125	49	128	51	253	0.19	0.53*
80	73	49	76	51	149
≤70	33	38	53	62	86

CARG: Cancer and Aging Research Group; ROC: receiver operating characteristic; KPS: Karnofsky performance status.
* Risk score and physician-rated KPS were treated as continuous to calculate the ROC.

From: Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011; 29:3457. Reprinted with permission. Copyright © 2011 American Society of Clinical Oncology. All rights reserved.

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خرید پکیج

Ability of CARG risk score versus physician-rated Karnofsky performance status (KPS) to predict chemotherapy toxicity