Available solutions | ||||
Albumin solutions | Starches¶ | |||
4, 5 percent | 20, 25 percent | 3, 6, 10 percent Hetastarch | 10 percent Pentastarch | |
Molecular weight, average (kD) | 69 | 69 | 450 | 280 |
Osmolality, mOsm/L | 290 | 310 | 300-310 | 326 |
COP, mm Hg | 20-30 | 70-100 | 23-50 | 23-50 |
Maximum volume expansion,* percent | 70-100 | 300-500 | 100-200 | 100-200 |
Duration of volume expansion, h | 12-24 | 12-24 | 8-36 | 12-24 |
Plasmatic half-life, h | 16-24 | 16-24 | 50 | 2-12 |
Potential for adverse reactions | + | + | ++ | ++ |
Possible side effects | Allergic reactions | Allergic reactions | Renal dysfunction | Renal dysfunction |
Transmitted infection | Transmitted infection | Coagulopathy | Coagulopathy | |
Pruritus | Pruritus | |||
Anaphylactoid reactions | Anaphylactoid reactions |
COP: colloid osmotic pressure.
* Expressed as a percentage of administered volume.
¶ Starches are rarely used due to increased mortality and renal dysfunction associated with their use.
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