Commercially available sources of quinine

Available forms of quinine:

Quinine sulfate capsules/tablets (as anti-malarial therapy or for leg cramps)

Quinine-containing beverages (eg, quinine water, tonic water, bitter lemon, gin and tonic)

Quinine is also added to other popular beverages because of its fluorescent properties (eg, "jello shots," "shocktails")

Herbal preparations containing quinine or bark from the Cinchona tree*

In the United States, quinine tablets are available only by prescription for the treatment of malaria (as Qualaquin). In other countries, quinine may be available for leg cramps by prescription or over-the-counter. We believe all of the products listed above have the potential for causing drug-induced immune thrombocytopenia (DITP) and/or immune-mediated drug-induced thrombotic microangiopathy (DITMA).

Adapted from: Liles NW, Page EE, Liles AL, et al. Diversity and severity of adverse reactions to quinine: a systematic review. Am J Hematol 2016; 91:461.

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Commercially available sources of quinine