Prevalence of community respiratory viruses in lung transplant recipients in studies that used molecular methods

Study:	Milstone^[1]	Gottlieb^[2]	Liu^[3]	Kumar^[4]	Soccal^[5]	Weinberg^[6]
Population:	50 adults 17 (34 percent) with infection	384 adults 30 (7.8 percent) with infection	576 children 79 (13.8 percent) with infection	93 adults 48 (51.6 percent) with infection	77 adults and children* 13 (17.2 percent) with infection^¶	60 adults 51 (85 percent) with symptoms
Influenza	10 (52.6 percent)	1 (2.9 percent)	9 (8.9 percent)	4 (4.9 percent)	1 (1.7 percent)	16 (25 percent)
Respiratory syncytial virus	8 (42.1 percent)	7 (20.5 percent)	21 (20.8 percent)	4 (4.9 percent)	7 (11.9 percent)	13 (20.3 percent)
Human metapneumovirus	-	6 (17.6 percent)	-	-	3 (5.1 percent)	7 (10.9 percent)
Parainfluenza virus	1 (5.3 percent)	12 (35.3 percent)	19 (18.9 percent)	17 (21.0 percent)	13 (22 percent)	19 (29.7 percent)
Rhinovirus	-	3 (6.6 percent)	22 (21.7 percent)	46 (56.8 percent)	22 (37.3 percent)	9 (14.1 percent)
Enterovirus	-	-	4 (3.9 percent)	-	-	-
Coronavirus	-	5 (17.1 percent)	-	11 (12.4 percent)	17 (28.8 percent)	-
Adenovirus	-	-	25 (25.8 percent)	-	-	-

* Majority were adults.
¶ Positive from bronchoalveolar fluid only.

References:

Milstone, AP, Brumble, LM, Barnes, J, et al. A single-season prospective study of respiratory viral infections in lung transplant recipients. Eur Respir J 2006; 28:131.
Gottlieb, J, Schulz, TF, Welte, T, et al. Community-acquired respiratory viral infections in lung transplant recipients: a single season cohort study. Transplantation 2009; 87:1530.
Liu, M, Worley, S, Arrigain, S, et al. Respiratory viral infections within one year after pediatric lung transplant. Transpl Infect Dis 2009; 11:304.
Kumar, D, Husain, S, Chen, MH, et al. A prospective molecular surveillance study evaluating the clinical impact of community-acquired respiratory viruses in lung transplant recipients. Transplantation 2010; 89:1028.
Soccal, PM, Aubert, JD, Bridevaux, PO, et al. Upper and lower respiratory tract viral infections and acute graft rejection in lung transplant recipients. Clin Infect Dis 2010; 51:163.
Weinberg, A, Lyu, DM, Li, S, et al. Incidence and morbidity of human metapneumovirus and other community-acquired respiratory viruses in lung transplant recipients. Transpl Infect Dis 2010; 12:330.

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