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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Clinical characteristics, classification, and presumed pathophysiology of neonatal seizures

Clinical characteristics, classification, and presumed pathophysiology of neonatal seizures
Focal clonic
Repetitive, rhythmic contracts of muscle groups of the limbs, face or trunk
May be unifocal or multifocal
May occur synchronously or asynchronously in muscle groups on one side of the body
May occur simultaneously, but asynchronously on both sides
Cannot be suppressed by restraint
Pathophysiology: epileptic
Focal tonic
Sustained posturing of single limbs
Sustained asymmetrical posturing of the trunk
Sustained eye deviation
Cannot be provoked by stimulation or suppressed by restraint
Pathophysiology: epileptic
Generalized tonic
Sustained symmetrical posturing of limbs, trunk and neck
May be flexor, extensor or mixed extensor/flexor
May be provoked or intensified by stimulation
May be suppressed by restraint or repositioning
Presumed pathophysiology: nonepileptic
Myoclonic
Random, single, rapid contractions of muscle groups of the limbs, face or trunk
Typically not repetitive or may recur at a slow rate
May be generalized, focal or fragmentary
May be provoked by stimulation
Presumed pathophysiology: may be epileptic or nonepileptic
Spasms
May be flexor, extensor, or mixed extensor/flexor
May occur in clusters
Cannot be provoked by stimulation or suppressed by restraint
Pathophysiology: Epileptic
Motor Automatisms
Described in table "Motor automatisms"
Sequential seizure
Variety of clinical signs occur in sequence with an individual seizure
May change in lateralization within or between seizures
Presumed pathophysiology: Genetic neonatal epilepsy

Adapted from: Mizrahi EM, Kellaway P. Diagnosis and Management of Neonatal Seizures. Lippincott-Raven, Philadelphia 1998.

Additional data from:

  1. Zuberi SM, Wirrell E, Yozawitz E, et al. ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia 2022; 63:1349.
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