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The timeline of infections following solid organ transplantation[1-3]

The timeline of infections following solid organ transplantation[1-3]
Common patterns of opportunistic infection are observed following solid organ transplantation based on epidemiologic exposures and the "net state of immunosuppression." The timeline is altered based on the immunosuppressive regimen and prophylactic medications. The dynamic assessment of infectious risk represents assays that will measure an individual's risk for infection due to specific pathogens or in general.
CMV: cytomegalovirus; EBV: Epstein-Barr virus; HSV: herpes simplex virus; MRSA: methicillin-resistant Staphylococcus aureus; PML: progressive multifocal leukoencephalopathy; PTLD: posttransplant lymphoproliferative disorder; SARS: severe acute respiratory syndrome; VRE: vancomycin-resistant enterococcus; VZV: varicella-zoster virus.
Modified from:
  1. Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007; 357:2601.
  2. Rubin RH, Wolfson JS, Cosimi AB, Tolkoff-Rubin NE. Infection in the renal transplant recipient. Am J Med 1981; 70:405.
  3. Fishman JA, Rubin RH. Infection in organ-transplant recipients [see comments]. N Engl J Med 1998; 338:1741.
From: Fishman JA, and the AST Infectious Diseases Community of Practice. Introduction: Infection in solid organ transplant recipients. Am J Transplant 2009; 9 (Suppl 4):S3. Copyright © 2009 American Society of Transplantation and the American Society of Transplant Surgeons. Reproduced with permission of John Wiley & Sons, Inc.
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