Genesis of Lepore and Kenya hemoglobins

These figures illustrate the unequal crossing-over which underlies the production of the Lepore and Kenya hemoglobins. For ease in understanding, each "newly created" gene has been given a separate color. Gene segments which are composed of joined portions from two different genes are shown in parentheses. Panel (A): unequal crossing-over between the beta gene locus of one chromosome and the delta gene locus of the other yields the genes for Lepore (red) and anti-Lepore (green) hemoglobins. Panel (B): unequal crossing-over between the beta gene locus of one chromosome and the A(gamma) gene locus of the other yields the genes for Kenya (red) and anti-Kenya (green) hemoglobins.