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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Treatment of individuals with onchocerciasis

Treatment of individuals with onchocerciasis
Individuals in endemic areas with high levels of ongoing transmission[1]
Ivermectin 150 mcg/kg orally (single dose); repeat every 3 to 6 months until asymptomatic
Individuals outside endemic areas or in areas with low transmission*
Ivermectin 150 mcg/kg orally (single dose), followed by:
Doxycycline 200 mg orally once daily for 6 weeks (start 1 week after administration of ivermectin)

* Most studies on the effectiveness of doxycycline consist of treatment with ivermectin for 4 to 6 months following treatment with doxycycline, so the safety of simultaneous treatment is unknown. To expedite symptomatic relief, we are in agreement with the United States Centers for Disease Control and Prevention, which favors treatment with ivermectin (150 mcg/kg orally single dose) 1 week prior to starting doxycycline[2]. For patients with persistent symptoms, ivermectin (single dose) may be repeated every 3 to 6 months until asymptomatic.

¶ Doxycycline is contraindicated during pregnancy.
References:
  1. Hoerauf A. Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis. Curr Opin Infect Dis 2008; 21:673.
  2. United States Centers for Disease Control and Prevention. Parasites – Onchocerciasis (also known as River Blindness). Available at: https://www.cdc.gov/parasites/onchocerciasis/health_professionals/index.html (Accessed on May 31, 2022).
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