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Aspergillus bronchopneumonia histopathology

Aspergillus bronchopneumonia histopathology
(Panel A) Magnified view of a slice of lower lobe shows multiple foci of necrosis, some clearly centered on airways (arrows) as indicated by their intimate association with pulmonary arteries. The lung parenchyma adjacent to the necrotic regions is hemorrhagic.
(Panel B) Photomicrograph shows small colonies of Aspergillus (arrow) within a bronchial lumen (L) and wall (W). Extension of fungus can also be seen into the adjacent pulmonary artery, which is partly occluded by thrombus (T). An infiltrate of neutrophils (N) is evident in the adjacent lung.
Reproduced with permission from: Müller NL, Fraser RS, Lee KS, Johkoh T. Pulmonary infections. In: Diseases of the Lung, Lippincott Williams & Wilkins, Philadelphia 2002. Copyright © 2002 Lippincott Williams & Wilkins. www.lww.com.
Graphic 57220 Version 12.0

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