Thin basement membrane disease

Electron micrograph comparing the thickness of the normal glomerular basement membrane (GBM; panel A) to the much thinner GBM in thin basement membrane disease (panel B).

Electron micrograph of a normal glomerular capillary loop showing the fenestrated endothelial cell (Endo), the glomerular basement membrane (GBM), and the epithelial cells with its interdigitating foot processes (arrow). The GBM is thin, and no electron-dense deposits are present. Two normal platelets are seen in the capillary lumen.