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Rome III diagnostic criteria* for irritable bowel syndrome

Rome III diagnostic criteria* for irritable bowel syndrome
Recurrent abdominal pain or discomfort at least three days per month in the last three months associated with two or more of the following:
(1) Improvement with defecation
(2) Onset associated with a change in frequency of stool
(3) Onset associated with a change in form (appearance) of stool
* Criteria fulfilled for the last three months with symptom onset at least six months prior to diagnosis.
¶ Discomfort means an uncomfortable sensation not described as pain. In pathophysiology research and clinical trials, a pain/discomfort frequency of at least two days a week during screening evaluation for subject eligibility.
Reproduced with permission from: Longstreth GF, Thompson WG, Chey WD, et al. Functional bowel disorders. Gastroenterology 2006; 130:1480.
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