Risk factors for neuraxis involvement by non-Hodgkin lymphoma

Stage III/IV disease*

Presence of B symptoms

Retroperitoneal lymph node involvement

Bone marrow involvement

Involvement of >1 extranodal site*

Elevated serum lactate dehydrogenase level*

Low serum albumin concentration

Age >60 years*

Aggressive or highly aggressive disease

High- or high-intermediate risk disease by the IPI#

Testicular involvement (see text for other primary sites)

Risk_neuraxis_involvement_N.htm

IPI: International Prognostic Index.
* Components of the IPI.

Graphic 54470 Version 2.0

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