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Peripheral blood smear in a patient with chronic lymphocytic leukemia

Peripheral blood smear in a patient with chronic lymphocytic leukemia
Blood smear from a patient with B cell chronic lymphocytic leukemia. The predominant lymphocytes have a very sparse cytoplasm, round to slightly oval nuclei, and no evident nucleoli. Damaged lymphocytes ("smudge cells") are present (arrows).
From: Brunning RD, McKenna RW. Tumors of the bone marrow. Atlas of tumor pathology (electronic fascicle), Third series, fascicle 9, 1994, Washington, DC. Armed Forces Institute of Pathology.
Graphic 54469 Version 3.0