Bronchoalveolar lavage: common cellular patterns in selected diseases

	Lymph	Neutro	Eosino	Mast cells	Other features
Inflammatory diseases
IPF	+	+++	+	N
PF-CTD	+	+	+	N	Increased lymphocytes in early disease
Cryptogenic organizing pneumonia	+	+	+	+/-	Foamy macrophages; mixed pattern of increased cells characteristic; decreased CD4:CD8 ratio
Eosinophilic pneumonia	+	N	++++
Asbestosis	N	++	+	N	Ferruginous bodies
Silica-exposed	+/-	N	N	N	Dust particles by polarized light microscopy
Coal workers' pneumoconiosis	+	+	N	N
Aluminum potroom workers	N	N	N	?	+ LTT
Granulomatous diseases
Sarcoidosis	++	N or +	N	N	CD4/CD8 ≥2
Hypersensitivity pneumonitis	+++	N or +	N	+	CD4/CD8 <1
Chronic beryllium disease	+++	N or +	N	N	+ LTT to beryllium salts

Cellular_patterns_in_BAL.htm

+: increase; N: normal values; lymph: lymphocytes; neutro: neutrophils; eosino: eosinophils; IPF: idiopathic pulmonary fibrosis; PF-CTD: pulmonary fibrosis associated with connective tissue disease; LTT: lymphocyte transformation test.

Graphic 54377 Version 1.0

خرید پکیج

Bronchoalveolar lavage: common cellular patterns in selected diseases