Proposed mechanisms for prone response

	Physiologic effect	Clinical result
Improved configuration between lung and thorax
Heart is dependent	More homogeneous Ppl gradient in ventrodorsal and cephalocaudal planes	Improved ventilation distribution
Smaller volume of dependent lung		Increased FRC (↓ shunt)
Abdomen is unsupported*
Secretion mobilization	Improved bronchial drainage	Improved ventilation
Improved aerosol delivery	Improved effect of aerosolized meds	Improved ventilation
More homogeneous perfusion	Less dependent perfusion	Improved V/Q matching (↓ shunt)

Ppl: Pleural pressure; FRC: functional residual capacity; V/Q: ventilation-perfusion.
* Assumes prone positioning with the upper chest and pelvis supported and the abdomen suspended.

Graphic 54334 Version 2.0

خرید پکیج

Proposed mechanisms for prone response