Lipoatrophy | Switch thymidine analogue (stavudine or zidovudine) to abacavir or tenofovir | Injectable fillers for facial lipoatrophy | Pioglitazone (in patients with insulin resistance) | | Fat accumulation | Diet and exercise | Metformin (in patients with diabetes mellitus) | Tesamorelin | Surgery (eg, liposuction of dorsocervical fat pad or reduction mammoplasty) | |