Large T cell lymphoma with reactive hemophagocytosis
The red pulp of the spleen is diffusely permeated by large lymphoma cells (T lineage, blue arrows) and histiocytes showing erythrophagocytosis (black arrow). The histiocytes have smaller, bland-looking nuclei with delicate chromatin.
From: Warnke RA, Weiss LM, Chan JK, et al. Tumors of the lymph nodes and spleen. Atlas of tumor pathology (electronic fascicle), Third series, fascicle 14, 1995, Washington, DC. Armed Forces Institute of Pathology.
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